Can I use
?

Brotli Accept-Encoding/Content-Encoding

- OTHER

More effective lossless compression algorithm than gzip and deflate.

Chrome

  1. 4 - 48: Not supported
  2. 49: Disabled by default
  3. 50: Supported
  4. 51 - 112: Supported
  5. 113: Supported
  6. 114 - 116: Supported

Edge

  1. 12 - 14: Not supported
  2. 15 - 112: Supported
  3. 113: Supported

Safari

  1. 3.1 - 10.1: Not supported
  2. 11 - 12.1: Supported
  3. 13 - 16.4: Supported
  4. 16.5: Supported
  5. 16.6 - TP: Supported

Firefox

  1. 2 - 43: Not supported
  2. 44 - 112: Supported
  3. 113: Supported
  4. 114 - 115: Supported

Opera

  1. 9 - 35: Not supported
  2. 36 - 37: Disabled by default
  3. 38 - 98: Supported
  4. 99: Supported

IE

  1. 5.5 - 10: Not supported
  2. 11: Not supported

Chrome for Android

  1. 113: Supported

Safari on iOS

  1. 3.2 - 10.3: Not supported
  2. 11 - 16.4: Supported
  3. 16.5: Supported

Samsung Internet

  1. 4: Not supported
  2. 5 - 20: Supported
  3. 21: Supported

Opera Mini

  1. all: Not supported

Opera Mobile

  1. 10 - 12.1: Not supported
  2. 73: Supported

UC Browser for Android

  1. 13.4: Supported

Android Browser

  1. 2.1 - 4.4.4: Not supported
  2. 113: Supported

Firefox for Android

  1. 113: Supported

QQ Browser

  1. 13.1: Supported

Baidu Browser

  1. 13.18: Supported

KaiOS Browser

  1. 2.5: Supported
  2. 3: Supported
Resources:
WebKit Bug 154859: Add support for format brotli for HTTP compression
Official code repository
Blink's intent to ship
Introducing Brotli