Can I use
?

CSS Initial Letter

- WD

Method of creating an enlarged cap, including a drop or raised cap, in a robust way.

Chrome

  1. ❌ 4 - 109: Not supported
  2. ◐ 110 - 136: Partial support
  3. ◐ 137: Partial support
  4. ◐ 138 - 140: Partial support

Edge

  1. ❌ 12 - 109: Not supported
  2. ◐ 110 - 136: Partial support
  3. ◐ 137: Partial support

Safari

  1. ❌ 3.1 - 8: Not supported
  2. ◐ 9: Partial support
  3. ◐ 9.1 - 18.4: Partial support
  4. ◐ 18.5: Partial support
  5. ◐ 26.0 - TP: Partial support

Firefox

  1. ❌ 2 - 138: Not supported
  2. ❌ 139: Not supported
  3. ❌ 140 - 142: Not supported

Opera

  1. ❌ 9 - 97: Not supported
  2. ◐ 98 - 116: Partial support
  3. ◐ 117: Partial support

IE

  1. ❌ 5.5 - 10: Not supported
  2. ❌ 11: Not supported

Chrome for Android

  1. ◐ 137: Partial support

Safari on iOS

  1. ❌ 3.2 - 8.4: Not supported
  2. ◐ 9 - 18.4: Partial support
  3. ◐ 18.5: Partial support
  4. ◐ 26.0: Partial support

Samsung Internet

  1. ❌ 4 - 20: Not supported
  2. ◐ 21 - 27: Partial support
  3. ◐ 28: Partial support

Opera Mini

  1. ❌ all: Not supported

Opera Mobile

  1. ❌ 10 - 12.1: Not supported
  2. ◐ 80: Partial support

UC Browser for Android

  1. ❌ 15.5: Not supported

Android Browser

  1. ❌ 2.1 - 4.4.4: Not supported
  2. ◐ 137: Partial support

Firefox for Android

  1. ❌ 139: Not supported

QQ Browser

  1. ❌ 14.9: Not supported

Baidu Browser

  1. ❌ 13.52: Not supported

KaiOS Browser

  1. ❌ 2.5: Not supported
  2. ❌ 3: Not supported
Resources:
WebKit bug to unprefix -webkit-initial-letter
Firefox Implementation Ticket
MDN Web Docs - CSS initial-letter
Demos at Jen Simmons Labs
Blog post on Envato Tuts+, "Better CSS Drop Caps With initial-letter"