Can I use
?

CSS Initial Letter

- WD

Method of creating an enlarged cap, including a drop or raised cap, in a robust way.

IE

  1. 5.5 - 10: Not supported
  2. 11: Not supported

Edge

  1. 12 - 84: Not supported
  2. 85: Not supported

Firefox

  1. 2 - 79: Not supported
  2. 80: Not supported
  3. 81 - 82: Not supported

Chrome

  1. 4 - 84: Not supported
  2. 85: Not supported
  3. 86 - 88: Not supported

Safari

  1. 3.1 - 8: Not supported
  2. 9: Partial support
  3. 9.1 - 13.1: Partial support
  4. 14: Partial support
  5. TP: Partial support

Opera

  1. 9 - 69: Not supported
  2. 70: Not supported

iOS Safari

  1. 3.2 - 8.4: Not supported
  2. 9 - 13.7: Partial support
  3. 14.0: Partial support

Opera Mini

  1. all: Not supported

Android Browser

  1. 2.1 - 4.4.4: Not supported
  2. 81: Not supported

Blackberry Browser

  1. 7: Not supported
  2. 10: Not supported

Opera Mobile

  1. 10 - 12.1: Not supported
  2. 46: Not supported

Chrome for Android

  1. 85: Not supported

Firefox for Android

  1. 79: Not supported

IE Mobile

  1. 10: Not supported
  2. 11: Not supported

UC Browser for Android

  1. 12.12: Not supported

Samsung Internet

  1. 4 - 11.2: Not supported
  2. 12.0: Not supported

QQ Browser

  1. 10.4: Not supported

Baidu Browser

  1. 7.12: Not supported

KaiOS Browser

  1. 2.5: Not supported
Resources:
Demos at Jen Simmons Labs
Firefox Implementation Ticket
MDN Web Docs - CSS initial-letter
Blog post on Envato Tuts+, "Better CSS Drop Caps With initial-letter"