Can I use
?

CSS font-size-adjust

- CR

Method of adjusting the font size in a matter that relates to the height of lowercase vs. uppercase letters. This makes it easier to set the size of fallback fonts.

IE

  1. 5.5 - 10: Not supported
  2. 11: Not supported

Edge

  1. 12 - 18: Not supported
  2. 79 - 85: Disabled by default
  3. 86: Disabled by default

Firefox

  1. 2: Not supported
  2. 3 - 80: Supported
  3. 81: Supported
  4. 82 - 83: Supported

Chrome

  1. 4 - 42: Not supported
  2. 43 - 85: Disabled by default
  3. 86: Disabled by default
  4. 87 - 89: Disabled by default

Safari

  1. 3.1 - 13.1: Not supported
  2. 14: Not supported
  3. TP: Not supported

Opera

  1. 9 - 29: Not supported
  2. 30 - 70: Disabled by default
  3. 71: Disabled by default

iOS Safari

  1. 3.2 - 13.7: Not supported
  2. 14: Not supported

Opera Mini

  1. all: Not supported

Android Browser

  1. 2.1 - 4.4.4: Not supported
  2. 81: Not supported

Blackberry Browser

  1. 7: Not supported
  2. 10: Not supported

Opera Mobile

  1. 10 - 12.1: Not supported
  2. 59: Not supported

Chrome for Android

  1. 85: Not supported

Firefox for Android

  1. 79: Not supported

IE Mobile

  1. 10: Not supported
  2. 11: Not supported

UC Browser for Android

  1. 12.12: Not supported

Samsung Internet

  1. 4 - 11.2: Not supported
  2. 12.0: Not supported

QQ Browser

  1. 10.4: Disabled by default

Baidu Browser

  1. 7.12: Not supported

KaiOS Browser

  1. 2.5: Not supported
Resources:
Article on font-size-adjust
MDN Web Docs - CSS font-size-adjust
Microsoft Edge feature request on UserVoice