Can I use
?

HTTP Live Streaming (HLS)

- UNOFF

HTTP-based media streaming communications protocol

Chrome

  1. ❌ 4 - 141: Not supported
  2. ✅ 142 - 156: Supported
  3. ✅ 157: Supported
  4. ✅ 158 - 160: Supported

Edge

  1. ✅ 12 - 18: Supported
  2. ❌ 79 - 155: Not supported
  3. ❌ 156: Not supported

Safari

  1. ❌ 3.1 - 5.1: Not supported
  2. ✅ 6 - 27.1: Supported
  3. ✅ 27.2: Supported
  4. ✅ 27.3 - TP: Supported

Firefox

  1. ❌ 2 - 158: Not supported
  2. ❌ 159: Not supported
  3. ❌ 160 - 162: Not supported

Opera

  1. ❌ 9 - 138: Not supported
  2. ❌ 139: Not supported

IE

  1. ❌ 5.5 - 10: Not supported
  2. ❌ 11: Not supported

Chrome for Android

  1. ✅ 157: Supported

Safari on iOS

  1. ✅ 3.2 - 26.6: Supported
  2. ✅ 27.0: Supported
  3. ✅ 27.1 - 27.2: Supported

Samsung Internet

  1. ✅ 4 - 30: Supported
  2. ✅ 31: Supported

Opera Mini

  1. ❌ all: Not supported

Opera Mobile

  1. ❌ 10 - 12.1: Not supported
  2. ✅ 80: Supported

UC Browser for Android

  1. ✅ 15.5: Supported

Android Browser

  1. ❌ 2.1 - 2.3: Not supported
  2. ✅ 3 - 4.4.4: Supported
  3. ✅ 157: Supported

Firefox for Android

  1. ✅ 159: Supported

QQ Browser

  1. ✅ 14.9: Supported

Baidu Browser

  1. ✅ 13.52: Supported

KaiOS Browser

  1. ❌ 2.5: Not supported
  2. ❌ 3: Not supported

HLS can be used with a JavaScript library in browsers that doesn't support it natively as long as they support Media Source Extensions.

Resources:
Apple developer article
Wikipedia article