Can I use
?

Mutation Observer

- LS

Method for observing and reacting to changes to the DOM. Replaces MutationEvents, which is deprecated.

Chrome

  1. 4 - 17: Not supported
  2. 18 - 26: Supported
  3. 27 - 116: Supported
  4. 117: Supported
  5. 118 - 120: Supported

Edge

  1. 12 - 116: Supported
  2. 117: Supported

Safari

  1. 3.1 - 5.1: Not supported
  2. 6: Supported
  3. 6.1 - 16.6: Supported
  4. 17.0: Supported
  5. 17.1 - TP: Supported

Firefox

  1. 2 - 13: Not supported
  2. 14 - 116: Supported
  3. 117: Supported
  4. 118 - 120: Supported

Opera

  1. 9 - 12.1: Not supported
  2. 15 - 101: Supported
  3. 102: Supported

IE

  1. 5.5 - 8: Not supported
  2. 9 - 10: Not supported (but has polyfill available)
  3. 11: Supported

Chrome for Android

  1. 117: Supported

Safari on iOS

  1. 3.2 - 5.1: Not supported
  2. 6: Supported
  3. 7 - 16.6: Supported
  4. 17.0: Supported
  5. 17.1: Supported

Samsung Internet

  1. 4 - 21: Supported
  2. 22: Supported

Opera Mini

  1. all: Not supported

Opera Mobile

  1. 10 - 12.1: Not supported
  2. 73: Supported

UC Browser for Android

  1. 15.5: Supported

Android Browser

  1. 2.1 - 3: Not supported
  2. 4 - 4.3: Not supported (but has polyfill available)
  3. 4.4 - 4.4.4: Supported
  4. 117: Supported

Firefox for Android

  1. 117: Supported

QQ Browser

  1. 13.1: Supported

Baidu Browser

  1. 13.18: Supported

KaiOS Browser

  1. 2.5: Supported
  2. 3: Supported

When changing the innerHTML content of a node containing a single CharacterData node, resulting in a single-but-different CharacterData child node, WebKit browsers consider this a characterData mutation of the child CharacterData node, while other browsers consider it a childList mutation of the parent node.

Resources:
MutationObserver from MDN
Polyfill