Can I use
?

WebUSB

- UNOFF

Allows communication with devices via USB (Universal Serial Bus).

Chrome

  1. ❌ 4 - 53: Not supported
  2. ❌ 54 - 60: Disabled by default
  3. ✅ 61 - 134: Supported
  4. ✅ 135: Supported
  5. ✅ 136 - 138: Supported

Edge

  1. ❌ 12 - 18: Not supported
  2. ✅ 79 - 134: Supported
  3. ✅ 135: Supported

Safari

  1. ❌ 3.1 - 18.3: Not supported
  2. ❌ 18.4: Not supported
  3. ❌ 18.5 - TP: Not supported

Firefox

  1. ❌ 2 - 136: Not supported
  2. ❌ 137: Not supported
  3. ❌ 138 - 140: Not supported

Opera

  1. ❌ 9 - 40: Not supported
  2. ❌ 41 - 47: Disabled by default
  3. ✅ 48 - 116: Supported
  4. ✅ 117: Supported

IE

  1. ❌ 5.5 - 10: Not supported
  2. ❌ 11: Not supported

Chrome for Android

  1. ✅ 135: Supported

Safari on iOS

  1. ❌ 3.2 - 18.3: Not supported
  2. ❌ 18.4: Not supported
  3. ❌ 18.5: Not supported

Samsung Internet

  1. ❌ 4 - 7.4: Not supported
  2. ✅ 8.2 - 26: Supported
  3. ✅ 27: Supported

Opera Mini

  1. ❌ all: Not supported

Opera Mobile

  1. ❌ 10 - 12.1: Not supported
  2. ✅ 80: Supported

UC Browser for Android

  1. ✅ 15.5: Supported

Android Browser

  1. ❌ 2.1 - 4.4.4: Not supported
  2. ❌ 135: Not supported

Firefox for Android

  1. ❌ 137: Not supported

QQ Browser

  1. ❌ 14.9: Not supported

Baidu Browser

  1. ✅ 13.52: Supported

KaiOS Browser

  1. ❌ 2.5: Not supported
  2. ❌ 3: Not supported
Resources:
Google Developers article
Mozilla Specification Positions: Harmful